Bioinformatics

ePromoters

Characterization of regulatory variants in promoters with enhancer activity and their relation with human diseases

RSAT variation-tools: An accessible and flexible framework to predict the impact of regulatory variants on transcription factor binding

Gene regulatory regions contain short and degenerated DNA binding sites recognized by transcription factors (TFBS). When TFBS harbor SNPs, the DNA binding site may be affected, thereby altering the transcriptional regulation of the target genes. Such …